Specialized software for simulating the multiple control and modulations of human hemodynamics

Most models of human hemodynamics describe only a small part physiological mechanisms that directly or indirectly alter activities the heart pump and vascular tones. Therefore, very narrow range tasks related to cardiovascular physiology can be solved using these models. To essentially widen this range, special software based on quantitative providing overall control circulation is created. In complex model, multi-compartmental lumped parametric model hemodynamics, provided under stable values blood volume parameters, forms core model. It consists two ventricles 21 compartments. Additional dynamic represent mechanoreceptor reflexes, chemoreceptor main effects angiotensin-II, antidi uretic hormone, vasopressin, adrenalin, cardiac brain ischemia. The has physiologist-oriented user interface. provides investigator with multiple capabilities for simulating different states each included mechanism. interface also allows creating arbitrary combinations chosen mechanisms. particular, activated deactivated via modulates initial Special opportunities have been created hypotheses concerning etiology arterial hypertension. Simulation results are presented graphs. documents simulation as file saved later independent analysis. software, in frame .NET technology, an autonomous .EXE executing PС. Software good computer program used educational purposes illustrating certain pathological regularities medical students.